Doesn't remove Curse of Darkness afflicted by XIX - The Sun?, no matter if Night Light was picked up before or after using the card.

This item is not recommended against The Beast, as the fires spawned by her will be slowed down significantly and pile up quickly, leading to no room to dodge.

Overuse of this effect can cause unavoidable patterns, as the slowed shots will often still travel most of their original distance.

Doing a quick circular motion is effective to slow surrounding enemy shots, especially while fighting Hush.

The light only needs to touch a shot once to slow it permanently.

Doesn't provide immunity on later floors, but lessens the visual effect significantly, effectively removing the curse.

Removes Curse of Darkness for the current floor.

The slow effect will disappear from enemies when the light stops shining on them, but shots will remain slow.

The light doesn't affect bosses, but it will slow their shots.

The light will face the direction Isaac is moving. Unsurprisingly, Edmund, Tyrone, and company got very angry when dataminers leaked the secrets of Rebirth.

A cone of light shines from Isaac's chest that slows all enemies and enemy shots.

Binding of isaac holy light